Hello,

How is it with vitamin K2 (menaquinone)? Is it produced by intestinal bacteria in the large intestine, and therefore can we say that the body produces this vitamin... or is its production negligible, and thus we generally say that the body does not produce any vitamins? I am also asking because of patients who take acenocoumarol and almost always have excessively thinned blood following antibiotic therapy.

Thank you for the response and guidance :)

Menachinon is produced by intestinal bacteria, and its primary function is to capture calcium from the extracellular environment and support its deposition into bones. The use of antibiotics damages the diversity and activity of the gut biome, which suppresses the production of anticoagulant factors - thus, during concurrent anticoagulant treatment, this effect is increased. According to studies, vitamin K2 does not affect blood coagulation; this role is fulfilled by vitamin K1, which is produced in the liver. The production of K2 by the intestinal microflora is significant and crucial, so any dysfunction of the gut biome in this context directly impacts hypercalcemia and manifests in the long term as bone demineralization.

In general, vitamins are defined as substances that the human body cannot produce on its own and must therefore be obtained through diet. This was true at the time the definition of this term was developed. Subsequently, other substances that do not conform to the original principles began to be included in this group—for example, those that do not contain an amino group (from which the name vitamin was derived by combining the words "vital" + "amine"), or those produced by the fermentative activity of microorganisms.

Themes:  Acenocoumarol