Good day.
In the lesson, you mentioned that liquid forms of vitamins do not have higher absorption rates than powders. Are there any studies on this? It mainly concerns fat-soluble vitamins like vitamin D. In the case of a tablet, you need to consume some fat for the vitamin to be absorbed correctly, whereas with a vitamin dissolved in oil – that is, in drops – this is not necessary.
Thank you for your response.

The issue of nutrient absorption is a complex problem, as the process is influenced by a variety of factors - the chemical form of the substance, its binding to substances that promote absorption, the combination of the supplement with food or its consumption on an empty stomach, the age of the user, their metabolic profile, and health status... Furthermore, there is a difference whether you simulate conditions in the laboratory (in vitro) or try to observe in living systems (in vivo) the rate and level of nutrient absorption from food or supplements based on their release into the bloodstream. Generally speaking, liquid forms of supplements are absorbed more quickly than tablet forms (due to the time-consuming nature of disintegration) - however, this information does not mean that they are absorbed better or in greater quantities, it only addresses speed. Tablet forms of supplements are generally recommended to be taken with meals, where, in relation to the content of fat-soluble substances, it is likely that the diet includes a certain amount of fats, which positively influences the absorption of these substances. At first glance, it might seem that the liquid form is more advantageous (and it is certainly faster) - typical examples are liquid forms with calciferol. However, this is only theoretical information based on the evaluation of the situation under in vitro conditions.

Themes:  Bioavailability